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Which class of antibodies is involved in immediate immune response?

  1. IgA

  2. IgE

  3. IgD

  4. IgM

The correct answer is: IgD

The class of antibodies integral to the immediate immune response is IgE. This type of antibody plays a critical role in the body’s defense against parasitic infections and is predominantly associated with allergic reactions. When an allergen enters the body, IgE antibodies bind to mast cells and basophils, leading to the release of histamines and other chemicals that trigger immediate inflammatory responses. While IgM is the first type of antibody produced in response to an infection, especially during the early stages, it is more involved in the initial detection of pathogens rather than the immediate allergic response. IgA primarily functions at mucosal surfaces, such as the respiratory and gastrointestinal tracts, providing localized defense. IgD's role is less understood but is thought to be involved in the initiation and regulation of B-cell activation and maturation, rather than immediate immune responses.